People suffering with chronic inflammation from periodontal
disease, heart disease, and arthritis, will find help in
recently-discovered compounds dubbed resolvins, according to research at
Boston University Goldman School of Dental Medicine.
The data suggests the key to controlling inflammation is the resolvins,
rather than the elimination of infection-causing bacteria, as previously
thought.
Additionally, if resolvins could be developed into a treatment, they offer
a safer option than other medications because the body produces resolvins
naturally.
Researchers found resolvins triggered both a drastic reduction in
inflammation and regeneration of bone and tissue destroyed by
periodontitis in rabbits with the disease.
The study, "Resolvin E1 Regulates Inflammation at the Cellular and Tissue
Level and Restores Tissue Homeostasis In Vivo," by Hatice Hasturk,
Alpdogan Kantarci, Emilie Goguet-Surmenian, Amanda Blackwood, Chris Andry,
Charles N. Serhan, and Thomas E. Van Dyke, appears online in the November
15 issue of the Journal of Immunology.
The mission of Boston University Goldman School of Dental Medicine is to
provide excellent education to dental professionals throughout their
careers; to shape the future of dental medicine and dental education
through research; to offer excellent health care services to the
community; to participate in community activities; and to foster a
respectful and supportive environment.
Boston University Goldman School of Dental Medicine
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